If we work with a strong will, we can overcome any difficulty, ______ great it is.

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问题 If we work with a strong will, we can overcome any difficulty, ______ great it is.

选项 A、what
B、how
C、however
D、whatever

答案C

解析 由于修饰的是形容词great,所以what(ever)都不能填入。而how是疑问副词,引出疑问句,或者用作感叹副词,引出感叹句,故也不能填入。however用于修饰程度已经很深的一些形容词,意为“无论多么…”,符合句意与语法,是正确答案。
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