______one time, Manchester was the home of the most productive cotton mills in the world.

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问题 ______one time, Manchester was the home of the most productive cotton mills in the world.

选项 A、On
B、By
C、At
D、Of

答案C

解析 at one time为固定词组,意义为“曾经”。句意是,曼彻斯特曾经是世界上最大的纺织厂基地。所以正确答案是C选项。
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