In the past 20 years alone, three coronaviruses have caused major disease outbreaks. First came the original SARS virus in 2002.

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问题     In the past 20 years alone, three coronaviruses have caused major disease outbreaks. First came the original SARS virus in 2002.【C1】________. in 2012, MERS was identified. In 2019, SARS-CoV-2【C2】________.
    Hundreds of other coronaviruses are known to be【C3】________in bats and other animals. Scientists have warned that some of them could arise in the future and【C4】________infect people. Our current COVID-19 vaccines were specifically【C5】________for SARS-CoV-2, but what if a next-generation vaccine could protect【C6】________both known and unknown coronaviruses?
    Scientists at the Walter Reed Army Institute of Research are working on a so-called universal coronavirus vaccine. Dr. Kayvon Modjarrad is【C7】________the effort. They have developed a vaccine specifically for SARS-CoV-2, and found that the immune response that it【C8】________is active against all the variants, as well as other coronaviruses like SARS-CoV-1. And this gives them confidence that it can be a platform for the entire coronavirus family.
    The vaccine is known as SpFN, which combines nanoparticles from ferritins with coronavirus spike proteins. But making the vaccine wasn’t as【C9】________as attaching one protein to another. Modjarrad and his colleagues had to【C10】________which parts of the spike to attach to which type of ferritin and how to【C11】________the two proteins together. It took months of trying more than 200 different【C12】________. By June of last year, the team found one version that succeeded where others had failed. They then【C13】________the experimental vaccine in mice and monkeys.
    The team also turned to less【C14】________animals for testing. Working with scientists in India, they【C15】________horses with the vaccine to learn how strong the【C16】________response was. And they【C17】________with Helen Dooley at the University of Maryland to vaccinate sharks—which make special antibodies.
    The results are【C18】________. but animals aren’t people. The Army vaccine is now being tested in a small, early-stage trial in humans.【C19】________it works and is safe, it could lay the【C20】________for a universal coronavirus vaccine.
【C7】

选项 A、leading
B、requiring
C、sparing
D、needing

答案A

解析 空格所在部分为Dr. Kayvon Modjarrad is________the effort,根据句意,空格处需要填入一个动词,与is一起构成谓语,引导宾语the effort。本句的前一句讲到,沃尔特.里德陆军研究所的科学家们正在研究一种通用冠状病毒疫苗,可见,the effort指代的就是这一疫苗的研究工作。Dr. Kayvon Modjarrad出现在疫苗研究工作之前,很可能就是该项目的负责人或带头人,四个选项中与此相对应的就是leading(领导,带领),故答案为选项A。B项意思是“要求”,C项意思是“节省;留出”,D项意思是“需要”,代入原文均不符合文意,故排除。
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