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There is evidence that the usual variety of high blood pressure is, in part, a familial disease. Since families have similar ge
There is evidence that the usual variety of high blood pressure is, in part, a familial disease. Since families have similar ge
admin
2011-07-28
34
问题
There is evidence that the usual variety of high blood pressure is, in
part, a familial disease. Since families have similar genes as well as similar
environments, familial diseases could be due to shared genetic influences,
to shared environmental factors, or both. For some years, the role of 1.______
one environmental factor commonly shared by families, namely dietary
salt (i.e., sodium chloride), has been studied at Brookhaven National
Laboratory. These studies suggest that chromic excess salt digestion 2.______
can lead to high blood pressure in man and animals. Some individuals,
however, and some rats consuming large amounts of salt without 3.______
developing high blood pressure. No matter how strictly all environmental
factors were controlled in these experiments, some salt-feeding animals 4.______
never developed hypertension although a few rapidly developed very 5.______
severe hypertension followed by early death. These marked variations were
interpreted to result from differences in genetic constitution.
By mating in successive generations only those animals that succeeded 6.______
to develop hypertension from salt ingestion, a resistant strain (the "R"
Strain) has been evolved in which consumption of large quantities of salt
fails to influence the blood pressure significantly. In contrast, by mating
only animals that quickly develop hypertension from salt, a sensitive strain
("S" strain) has also been found. 7.______
The availability of these tow strains permits investigations not
heretofore possible. They provide a feasible laboratory model which to 8.______
investigate some clinical aspects of the human prototypes of hypertension.
More important, there might be the possibility of developing methods by 9.______
which genetic susceptibility of human beings to high blood pressure can be
defined without waiting for its appearance. Radioactive sodium 22 was an
important "tool" in working for the characteristics of the sodium chloride. 10.______
选项
答案
succeeded——failed
解析
本题为逻辑错误。根据下文提到一种抗体基因R从这些老鼠体内提炼出来,这种抗体使大量摄入食盐无法影响血压。可见这些老鼠是没得高血压的老鼠,故用failed。
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