She was, ______her fame and fortune, basically an unhappy woman.

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问题 She was, ______her fame and fortune, basically an unhappy woman.

选项 A、despite from
B、however
C、in spite of
D、even though

答案C

解析 句意:尽管有名气和金钱,但她实际上不幸福。in spite of虽然,尽管。despite虽然;不管,不顾,但没有despite from的搭配。however然而,但是。even though尽管,虽然,引导让步状语从句。
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