Mr. Smith will be________the office next week when the manager is away.

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问题 Mr. Smith will be________the office next week when the manager is away.

选项 A、in charge of
B、in response to
C、in relation to
D、in place of

答案A

解析 in charge of:负责;in response to:作为对……的答复、响应;in relation to:关于,与……相比;in place of:代替,顶替。注意区分in charge of和in the charge of,这两个短语都可表示“由……负责、照顾、掌管”。但in charge of后面跟被照管的人或物,in the charge of后面则跟照管的人。根据句意可知,选A。
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