首页
外语
计算机
考研
公务员
职业资格
财经
工程
司法
医学
专升本
自考
实用职业技能
登录
外语
A Food and Drug Administration( FDA) advisory committee has concluded that a novel new treatment can greatly help rheumatoid art
A Food and Drug Administration( FDA) advisory committee has concluded that a novel new treatment can greatly help rheumatoid art
admin
2022-05-19
31
问题
A Food and Drug Administration( FDA) advisory committee has concluded that a novel new treatment can greatly help rheumatoid arthritis patients.
The panel recommended approving Enbrel for use alone in patients who haven’t responded to other drugs or in combination with methotrexate, a cancer drug that has been the main treatment for rheumatoid arthritis.
The FDA must make a final decision by early November, and the drug’s maker says it could be on the market by year’s end.
In rheumatoid arthritis, which affects 2. 1 million Americans, the immune system attacks healthy joints. A major wrongdoer in this process is a protein called "tumor killing factor", or TNF, which interacts with a special molecule, or TNF receptor, on cells’ surfaces.
To keep inflammation in check, cells normally release some receptors to mop up excess TNF, rendering it inactive. Apparently, rheumatoid arthritis patients don’t have enough free-floating TNF receptors.
Enbrel consists of genetically engineered TNF receptors. In a six-month study, 234 patients with advanced rheumatoid arthritis received one of two doses of Enbrel or a placebo (harmless substance given as if it were medicine) in twice-a-week injections. They took injections for six months. By the end, 40% of patients on the larger Enbrel dose saw symptoms, such as swelling and joint pain, cut in half. Only 5% on the placebo did that well. The main side effect was minor irritation at the injection site.
Because some TNF is needed for a normal immune response, there is at least a theoretical risk of infections or even cancer in patients who take Enbrel, so the FDA panel urged long-term safety studies.
Last week, the FDA approved Arava, an oral treatment for rheumatoid arthritis that is similar to methotrexate. While calling both Enbrel and Arava "potentially very important", Brian Butcher, vice president for research at the Arthritis Foundation, notes they have been tested in relatively few patients.
Butcher says their safety should be closely monitored once they’re widely available.
Which of the following might be an appropriate title for the text?
选项
A、TNF and Immune System
B、Enbrel versus Methotrexate
C、Arthritis Drug on Path to Approval
D、Study on Rheumatoid Arthritis
答案
C
解析
全篇文章介绍一种治疗风湿性关节炎的新药恩利的药理作用以及可能造成的风险,并说明由于新药的风险。食品药品管理局对于审批十分谨慎,敦促进行长期的安全性研究。C项“关节炎药物的审批之路”涵盖了文章的主要内容,为正确选项。
转载请注明原文地址:https://jikaoti.com/ti/PnGsFFFM
本试题收录于:
公共英语四级笔试题库公共英语(PETS)分类
0
公共英语四级笔试
公共英语(PETS)
相关试题推荐
Thegovernmentistobanpaymentstowitnessesbynewspapersseekingtobuyuppeopleinvolvedinprominentcases【21】______
Thegovernmentistobanpaymentstowitnessesbynewspapersseekingtobuyuppeopleinvolvedinprominentcases【21】______
Thegovernmentistobanpaymentstowitnessesbynewspapersseekingtobuyuppeopleinvolvedinprominentcases【21】______
WherewasthedestinationofTitanic?
Inflationhasjustexploded.Therealproblemisthatwehaveanunderlyingrateofinflation—animpetusofwageschasingprices
In1987,therewereover1.5millionviolentcrimesreportedintheUnitedStates.Mostofthisviolencecomesfromaggressivep
Manydoctorssuspectthattheremaybesomerelationshipbetweenemotionsandillness.However,theycannotfindaproof.Itis
Onlythreestrategiesareavailableforcontrollingcancer:prevention,screeningandtreatment.Lungcancercausesmoredeaths
61)Fathersexposedtopoisonoussubstancesareprobablyjustaslikelytobethecauseofdefectsintheirunborninfantsasmot
1,050pounds
随机试题
反补贴措施包括___________、___________和___________。
第一审行政判决书的理由部分应当写明哪些内容?
临床上诊断劳力型心绞痛最重要的依据是
lac操纵子结构基因的表达条件是
推拿法治疗头痛常选用的穴位不包括
水运工程施工监理合同管理的内容包括()。
以人为本是中国共产党根本宗旨和执政理念的集中体现。()
一年级有2个班,男女生人数比是4:3,一班男女生人数比为3:4,二班男女生人数比为5:2。问一班、二班男生人数比是多少?()
AnnualGrammyAwards
中华人民共和国的成立和“社会主义改造”的完成,意味着中国人民选择并成功走上了社会主义道路。从社会发展的历史选择性的角度看,中国人民走上社会主义道路,其原因在于
最新回复
(
0
)