American this year will swallow 15, 000 tons drugs of aspirin, one of safest and most effective invented by man.

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问题    American this year will swallow 15, 000 tons drugs of
aspirin, one of safest and most effective invented by man.                 【M1】 ______
The most popular medicines in the world today, it is an ef-                【M2】 ______
fective pain reliever. Its bad effects are relatively mild, and it
is cheap.
   For millions of people suffered from arthritis, it is the               【M3】 ______
only thing that works. Aspirin, in short, is truly the 20th -
century wonder drug. It is also the second largest suicide
drug and is the leading cause of poisoning between chil-                   【M4】 ______
dren. It has side effects that, if relatively mild, are largely            【M5】 ______
unrecognized among users.
   Although aspirin was first sold by a German company
in 1899, it has been around more longer than that. Hippocra-
tes, in ancient Greece, understood the medical value of the
leaves and tree bark which today are known to contain salic -              【M6】 ______
ylates(水杨酸盐), the chemical in aspirin. During the 19th
century,there was a great number of experimentation in Eu-                 【M7】 ______
rope with this chemical and it led in the introduction of aspi-
rin. By 1915, aspirin tablets were available in the United                 【M8】 ______
States.
   A small quantity of aspirin (two five - grain tablets)
relieves pain and inflammation. It also reduces down fever                 【M9】 ______
by interfering with some of the body’s reactions. Specifical-
ly, aspirin seems to slow down the formation of the acids in-
volved in pain and the complex chemical reactions that
cause fever. The chemistry of these acids is not fully under-
stood, and the slowing effect of aspirin is well known.                   【M10】 ______
【M8】

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答案改“in”为“to”

解析 这里是一个固定词组“lead to”(导致)。
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