The operation known as a hemispherectomy—the removal of half the brain-sounds too radical to ever consider, much less perform. I

admin2022-08-06  47

问题     The operation known as a hemispherectomy—the removal of half the brain-sounds too radical to ever consider, much less perform. In the past century, however, surgeons have done it hundreds of times for disorders that cannot be controlled any other way. Perhaps surprisingly, the surgery has no apparent effect on personality or memory. Does that mean a person needs only half a brain? Yes and no. People can survive and function pretty well after the procedure, but they will have some physical disabilities.
    The first known hemispherectomy was performed on a dog in 1888 by German physiologist Friedrich Goltz. Neurosurgeon Walter Dandy pioneered the use of the procedure on humans at Johns Hopkins University in 1923, operating on a patient who had a brain tumor. That man lived for more than three years before ultimately dying from cancer.
    In 1938, after performing a hemispherectomy on a 16-year-old girl, Canadian neurosurgeon Kenneth McKenzie reported that it could stop seizures, a neurological disorder in the brain. And today brain surgeons perform hemispherectomies on patients who undergo dozens of seizures daily that resist all medication and stem from conditions that primarily afflict one hemisphere. "These disorders are often progressive and damage the rest of the brain if not treated," explains neurosurgeon Gary W. Mathern of the University of California, Los Angeles.
    The surgery takes two forms. Anatomical hemispherectomies involve the removal of an entire hemisphere, whereas functional hemispherectomies take out only parts of a hemisphere—as well as severing the connections between the two halves of the brain. Doctors often prefer anatomical hemispherectomies because "leaving even a little bit of brain behind can lead seizures to return," says neurologist John Freeman of Johns Hopkins, which specializes in the procedure. On the other hand, functional hemispherectomies, which U.C.L.A. surgeons usually perform, lead to less blood loss. "Our patients are usually under two years of age, so they have less blood to lose," Mathern says. Neurosurgeons have performed the functional operation on children as young as three months old. In these tiny patients, memory and personality develop normally.
    Most Johns Hopkins hemispherectomy patients are older than five years. A recent study found that 86 percent of the 111 children who underwent the procedure at Johns Hopkins between 1975 and 2001 are either seizure-free or have non-disabling seizures that do not require medication. Another study found that children who underwent a hemispherectomy often improved academically once their seizures stopped. "One was champion bowler of her class, one was chess champion of his state, and others are in college doing very nicely," Freeman notes.
Doctors prefer anatomical hemispherectomy to functional hemispherectomy in that

选项 A、it can completely stop seizures by removing the entire hemisphere.
B、it is harmful to sever the connections between the two halves of the brain.
C、the patients are old enough to bear the pain of the operation.
D、anatomical hemispherectomy causes less blood loss.

答案A

解析 考查因果细节,根据题干定位到第四段,其中讲到如果不完全切除大脑半球,就算只有极少的残余也会导致癫痫复发。故A项正确。B项中的it is harmful以及C项中的old enough to在文中并未提及;D项与文意相悖。原文说是功能性大脑半球切除术的病人失血量更少。
转载请注明原文地址:https://jikaoti.com/ti/Dmg7FFFM
0

最新回复(0)